Thyroid cancer represents about 4% of all new cancer cases. While it can be scary, most thyroid cancers are highly treatable and in some cases curable with treatment. The thyroid is at the front of the neck near the base of the throat. The thyroid gland is part of the endocrine system, which is a group glands that produce hormones that regulate many bodily functions. The thyroid specifically affects heart rate, blood pressure, temperature and metabolism.
Types
The four types of thyroid cancer are categorized by their cell of origin and their characteristics. Cancers arise from cells that have transformed and begun to abnormally divide and multiply.
- Papillary (PTC)
- Most common type: 70-80% are papillary thyroid cancer
- More common in females (3x more effected than males)
- Follicular (FTC)
- Makes up about 10-15% of thyroid cancers
- More common in females (3x more effected than males)
- Medullary (MTC)
- More likely to run in families
- 5-10% of thyroid cancers
- Develops from C Cells or parafolicullar cells which produce calcitonin (regulates calcium, phosphate)
- Anaplastic (ATC)
- Very rare, less than 2% of thyroid cancers
- Usually occurs in patients 65+ years
Diagnosis
Your doctor will review your medical history including your family’s medical history, and your doctor will review your history and tests along with your reported symptoms. Initial tests include blood work and a physical exam to check your thyroid gland and surrounding tissues. Other tests include thyroid scans to capture images of the gland and fine needle aspiration (FNA). A few other imaging studies may be used such as CT or MRI scans to help confirm diagnoses. Depending on a tumor’s characteristics, a laryngosopy may also be performed, which is a flexible tube used to examine your layrnx.
After a complete evaluation, your doctor will make a diagnosis and outline a treatment plan.
Treatment
Treatment for thyroid cancer will first be determined by the stage it’s in, which enables your doctor to develop the most effective plan. Thyroid cancer usually includes surgery, though the type of surgery varies depending on a patient’s health and the size of the tumor. Some options are:
- Thyroidectomy
- This procedure involves removing either partial sections of the thyroid gland, or the whole thyroid.
- Radioactive Iodine Therapy (RIA or RRA)
- RIA therapy involves a doctor administering iodine, typically in pill-form. The thyroid cells are the main cell that absorb iodine in your body, and by absorbing the iodine, it destroys remaining cancer cells and thyroid tissues that may remain after a thyroidectomy. Other cells are not effected. With traditional RIA, hypothyroidism occurs because patients aren’t able to continue taking thyroid hormone medications. Symptoms of hypothyroidism include fatigue, depression, forgetfulness, dry skin, constipation, difficulty walking, and forgetfulness.
- RIA with Thyrogen
- Prior to radioactive idodine therapy, the drug Thyrogen may be administered, which allows patients to continue taking their hormone replacement medications throughout RIA treatments. By doing so, patients won’t experience all the hypothyroidism symptoms during their treatment. Thyrogen is also sometimes used to test for cancer recurrence.
- Radiation Therapy
- Radiation therapy is rarely used for thyroid cancer, but in some situations may be called for. The goal is to kill cancer cells, shrink tumors, and relieve symptoms.
- Chemotherapy
- Chemotherapy uses drugs that kill cancerous cells but also kills normal cells. Chemo is rarely used for thyroid cancers except in aggressive cases such as anaplastic thyroid cancer.
- Whole-Body Thyroid Scan
- Whole-body scans may be performed in conjunction with other tests to monitor therapy progress and detect if the cancer has spread.
Followup Care
The prognosis for patients with thyroid cancer is often good, especially for those under the age of 45, those with small cancers, or papillary thyroid cancers when the tumors are confined to particular areas. But it’s critical for you to periodically follow-up with your doctor to ensure any recurrences or issues are caught immediately. Your doctor will discuss with you how frequent you will need follow-up appointments.
Follow-up care includes keeping up with any medical history updates, physical examinations, ultrasounds, FNA, blood tests, and other imaging tests as your doctor recommends.
Prepare for Your Appointment
Oftentimes so much information is shared between you and your doctor, it can be difficult to recall all the details later. It’s a great idea to bring a friend or family member along with you, keep a notebook during your appointments and even during your treatments to keep track of your experiences and symptoms. Write down questions you may have ahead of time, and then you’ll be able ensure you ask everything you intended to and be able to reference your notes.